Gene ABCD4

All Male only Female only
Location (GRCh37):
chr14:74,752,126-74,769,759
Description:
ATP-binding cassette, sub-family D (ALD), member 4 [Source:HGNC Symbol;Acc:68]
Biotype
Protein coding
Nb components:
10
Ensembl:
ENSG00000119688
HGNC Symbol:
68
MIM gene:
603214
MIM disease:
614857
Uniprot:
O14678, E9PI46, E9PPB6, H0YJ78, H0YJL8, H0YCY9, H0YJ82, H0YJX8, G3V3W1, G3V4U7
WikiGene:
5826
Median gene-level TPM by tissue (GTEx) [link]:

This plot shows tissues where the current gene is most expressed in GTEx to help contextualize phenotype associations.

Genetic associations QQ-plot

Inflation factor 𝜆=

Loading

This plot shows the distribution of observed association P-values compared to the expected distribution under the null hypothesis of no association (uniform distribution of P-values). Systematic deviation from the shaded region indicates statistical inflation that could be explained by pleiotropy.

Continuous variables

Outcome Id Description N -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Values noted as 0 represent values smaller than the numerical floating point representation limit (< 2e-308 for this analysis).

Cardiovascular Endpoints

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Self Reported

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading

Phecodes

Outcome Id Description N cases N controls N excluded from controls -log10(P) P-Value P-Value (Bonferroni) Q-Value
Loading